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A) DLS measurements of freshly prepared (full colored bars) and redispersed (shaded colored bars) LNPs. PDI is indicated by black squares. LNP formulations with neutral, positive or negative charge and spray dried (SD) 5% lactose were redispersed in HPW after spray drying at 62°C outlet temperature and compared to freshly prepared LNPs in 5% lactose solution. B) Zeta potential measurements of fresh and spray dried LNPs in 5% lactose solution via LDA. Mean ± standard deviation, n=3.
