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. 2022 Aug 29;77(11):3110–3117. doi: 10.1093/jac/dkac290

Table 2.

Spearman’s rank-order correlations for dolutegravir AUC0-24 estimates and change in modified mini screen score and sleep quality form baseline to weeks 4, 12, and 24

Spearman’s rank-order correlation for dolutegravir AUC0-24 and change in MMS from baseline Spearman’s rank-order correlation for dolutegravir AUC0-24 and change in sleep quality from baseline
Timepoint n rs 95% CI P value n rs 95% CI P value
Week 4 461 −0.062 −0.153 to +0.029 0.186 419 −0.036 −0.127 to 0.056 0.468
Week 12 461 −0.099 −0.188 to −0.011 0.033 411 −0.101 −0.201 to −0.001 0.041
Week 24 461 −0.129 −0.222 to −0.036 0.006 418 0.002 −0.098 to 0.101 0.968

AUC0-24, area under the concentration-time curve; MMS, modified mini score; rs, Spearman’s rank-order correlation.