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. Author manuscript; available in PMC: 2023 Apr 24.
Published in final edited form as: Nat Neurosci. 2022 Oct 24;25(11):1505–1518. doi: 10.1038/s41593-022-01179-2

Extended Data Figure 9. BLA is required to develop altruistic preference.

Extended Data Figure 9

a, Latency to respond (in sec) grouped by altruistic and selfish choices in control (light and dark orange, n=7) and hM4D mice (light and dark fuchsia, n=7) during the five days of SDM task (two-way ANOVA, group (control, hM4D, altruistic, selfish), x time (days 1-5), F(12, 96)=2.39, p=0.0093). b, Number of altruistic choices over 40 minutes of testing during the five days of the SDM in control and hM4D mice (mixed model analysis for each day of testing, day1: (control, hM4D) x time (min), F(16, 132)=0.48, p=0.9915; day 2: group F(42, 267)=0.42, p=0.9994; day 3: F(73, 685)=2.85, p<0.0001; day 4: F(80, 716)=2.13, p<0.0001; day 5: F(77, 696)=0.85, p=0.8057). c, Decision preference score in the five days of SDM and following one additional week of testing (day 13) in control (n=7) and hM4D (n=7) mice (two-way RM ANOVA, group (control, hM4D) x time (days), F(5, 60)=2.875, p=0.0416). d, Number of altruistic and selfish choices on test day 13 of the SDM in control (n=7) and hM4D (n=7) mice (two-way RM ANOVA, group (control, hM4D) x choice (altruistic, selfish), F(1, 12)=9.661, p=0.0091). *p<0.05, **p<0.01, ***p<0.001. Values are expressed as mean ± s.e.m.