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. Author manuscript; available in PMC: 2023 Apr 24.
Published in final edited form as: Nat Neurosci. 2022 Oct 24;25(11):1505–1518. doi: 10.1038/s41593-022-01179-2

Figure 3. Mice display more selfish choices with unfamiliar recipients.

Figure 3

a, Decision preference score in the five days of SDM in mice tested with familiar (orange, n=13, males/females 7/6) or unfamiliar (green, n=15, males/females 10/5) recipients (two-way RM ANOVA, group (familiar recipient, unfamiliar recipient) x time (days 1-5), F(4, 104)=2.707, p=0.0342). b, Number of nose poke responses in the condition with familiar (black border, n=13) and unfamiliar recipient (green border, n=15; two-way RM ANOVA, group (familiar, unfamiliar) x response (altruistic, selfish), F(1, 52)=12.03, p=0.0011). c, Individual decision preference score in the SDM in mice tested with familiar or unfamiliar recipients and number of mice tested with an unfamiliar recipient (chi-square test, χ2=5.99, p=0.0143). Mice were assigned to altruistic (orange), selfish (blue) or no preference (grey) using one sample t-test to chance (50%, red line). d, Individual decision preference score in mice tested with unfamiliar recipients (n=15) grouped by preference and change from preference (expressed in %, (n=12) in the SDM with altruistic choices reinforced on FR2 and FR4. *p<0.05, **p<0.01, ***p<0.001. n.s. not significant. Values are expressed as mean ± s.e.m.