Fig. 1. Correlation between polarizable simulation and their scale factors.

S^eff (black full circle) is based on the reduction of Coulombic interaction between non-polarized (non-scaled) and the polarized system. S^∈_∞ (gray circles) is computed by $1/\sqrt{{\in }_{\infty }}$. The charge-reduced simulation with a scaling factor of S^eff = 0.90, 0.85, 0.80 and 0.74 correspond to a polarizable system with 39.4%, 58.6%, 77.9% and 100% polarizability, respectively.