Associations of genetically predicted circulating vitamin C levels with risk of cardiovascular disease. CARDIoGRAMplusC4D, Coronary ARtery DIsease Genome-wide Replication and Meta-analysis plus The Coronary Artery Disease Genetics; CVD, cardiovascular disease; HERMES; Heart Failure Molecular Epidemiology for Therapeutic Targets; ISGC, International Stroke Genetic Consortium; LB, lower bound of 95% confidence interval; OR, odds ratio; UKBB, UK Biobank; UB, upper bound of 95% confidence interval. The UK Biobank was included in the GWAS meta-analysis for atrial fibrillation (Nielsen et al.), HERMES consortium, and ISGC.