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. Author manuscript; available in PMC: 2022 Nov 30.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Feb 9;1867(4):159121. doi: 10.1016/j.bbalip.2022.159121

Fig. 2. Increased CM-TC secretion in HF/HCD-fed Atgl iTg mice.

Fig. 2

Atgl iTg and control mice were fasted for 4 h prior to i.p. administration of tyloxapol. Secretion of CM-TG and CM-TC 2.5 and 5 h after an oral lipid bolus containing [3H]-triolein and [14C]-cholesterol in (A) chow diet- and (B) 5-week HF/HCD-fed WT and Atgl iTg mice. (C, D) VLDL-TG and VLDL-TC concentrations measured before, 2, 4, and 6 h after the administration of tyloxapol in (C) chow diet- and (D) 5-week HF/HCD-fed mice. (E) Plasma cholesterol levels in chow diet-fed mice under various feeding conditions. Data represent mean values of 16-21 week-old female mice (n=3-7) ± SD. * p < 0.05; ** p ≤ 0.01; *** p ≤ 0.001.