Table 1.
Incidence of diabetes by sex, age-group, period, and BMI category for patients with DS and control patients
| DS | Control | |||||
|---|---|---|---|---|---|---|
| Diabetes diagnoses | Person-years at risk | Incidence rate per 1,000 person-years (95% CI) | Diabetes diagnoses | Person-years at risk | Incidence rate per 1,000 person-years (95% CI) | |
| Total | 287 | 83,160.5 | 3.45 (3.06–3.87) | 1,254 | 389,136.1 | 3.22 (3.05–3.41) |
| Period | ||||||
| 1990–1999 | 15 | 11,602.1 | 1.29 (0.72–2.13) | 71 | 60,947.0 | 1.16 (0.91–1.47) |
| 2000–2009 | 122 | 37,480.8 | 3.26 (2.70–3.89) | 550 | 180,986.6 | 3.04 (2.79–3.30) |
| 2010–2020 | 150 | 34,077.6 | 4.40 (3.73–5.17) | 633 | 147,202.5 | 4.30 (3.97–4.65) |
| Sex | ||||||
| Male | 137 | 38,770.7 | 3.53 (2.97–4.18) | 617 | 190,023.8 | 3.25 (3.00–3.51) |
| Female | 150 | 44,389.8 | 3.38 (2.86–3.97) | 637 | 199,112.3 | 3.20 (2.96–3.46) |
| Age-group, years | ||||||
| 0–4 | 1 | 6,104.5 | 0.16 (0.00–0.91) | 4 | 33,986.7 | 0.12 (0.03–0.30) |
| 5–14 | 20 | 12,916.8 | 1.55 (0.95–2.39) | 25 | 65,148.9 | 0.38 (0.25–0.57) |
| 15–24 | 34 | 12,379.2 | 2.75 (1.90–3.84) | 38 | 56,126.1 | 0.68 (0.48–0.93) |
| 25–34 | 57 | 14,750.9 | 3.86 (2.93–5.01) | 87 | 52,598.1 | 1.65 (1.32–2.04) |
| 35–44 | 77 | 16,366.0 | 4.70 (3.71–5.88) | 186 | 63,677.5 | 2.92 (2.52–3.37) |
| 45–54 | 61 | 13,704.9 | 4.45 (3.40–5.72) | 356 | 64,138.6 | 5.55 (4.99–6.16) |
| 55–64 | 32 | 6,006.0 | 5.33 (3.64–7.52) | 384 | 39,821.9 | 9.64 (8.70–10.66) |
| 65–75 | 5 | 932.1 | 5.36 (1.74–12.52) | 174 | 13,638.2 | 12.76 (10.93–14.80) |
| BMI category | ||||||
| Underweight | 4 | 895.5 | 4.47 (1.22–11.44) | 2 | 4,450.8 | 0.45 (0.05–1.62) |
| Normal weight | 31 | 12,408.2 | 2.50 (1.70–3.55) | 133 | 53,086.0 | 2.51 (2.10–2.97) |
| Overweight | 51 | 12,053.3 | 4.23 (3.15–5.56) | 306 | 41,988.1 | 7.29 (6.49–8.15) |
| Obese | 148 | 18,334.7 | 8.07 (6.82–9.48) | 678 | 38,601.2 | 17.12 (15.86–18.46) |
| Not recorded | 53 | 39,468.8 | 1.34 (1.01–1.76) | 135 | 250,010.0 | 0.54 (0.45–0.64) |