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. 2022 Sep 7;27(11):4502–4509. doi: 10.1038/s41380-022-01733-1

Fig. 2. The effect of genotype, sex and citalopram plasma concentrtion on serotonin transporter occupancy.

Fig. 2

a Approximately one hour after infusion of 8 mg citalopram, lower serotonin transporter occupancy was observed in ABCB1rs2235015 minor allele carriers (A + AC) compared to major allele homozygotes (C) and female compared to male participants. b SERT occupancy is plotted against the area under the curve (AUC) of citalopram in plasma. Regression lines are plotted for participants grouped according to ABCB1rs2235015 genotype. Grey ribbons indicate 95% confidence intervals.