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. Author manuscript; available in PMC: 2022 Dec 10.
Published in final edited form as: Biomaterials. 2022 Jan 4;281:121363. doi: 10.1016/j.biomaterials.2022.121363

Fig. 4. Relative gene expression analysis of type I, type II BMP receptors and β-integrins.

Fig. 4

Data corresponding to (a) C2C12 cells and to (b) hPDSCs. The gene expression was analyzed by qPCR and it was normalized to the expression of EF1, PPIA and GUSB genes. Data are represented as mean + SEM of three independent experiments. (c) Table of the affinity constants (Kd in nM) of the type I and II BMP receptors with the four selected BMPs. Data was obtained from kinetic experiments performed by bio-layer interferometry (BLI), from the work of Khodr et al. [46]. The highest affinity couples (Kd < 5 nM) are highlighted in dark blue, those with an affinity in the range from 5 to 25 nM are in light blue. N.A means no measurable interaction. Values are given as mean ± SD of three independent experiments.