Table 1. Number of morbidity and mortality events by ICD-10 chapter and their overall associations with ever-regular smoking, for men and women combined.

						No. of significant associations
						Without FDR adjustment				With FDR adjustment
		No. of diseases		No. of cases		Positive		Inverse		Positive		Inverse
ICD-10 Chapter		Incidence	Death	Incidence	Death	Incidence	Death	Incidence	Death	Incidence	Death	Incidence	Death
I	Infectious and parasitic	21	4	28,572	624	3	1	0	0	1	0	0	0
II	Neoplasms	72	22	59,716	15,811	18	9	0	0	14	7	0	0
III	Blood and immune-related	7	1	6,146	90	0	0	1	0	0	0	0	0
IV	Endocrine, nutritional and metabolic	13	2	47,809	1,397	5	0	0	0	3	0	0	0
V	Mental and behavioural	12	4	8,109	140	0	0	2	0	0	0	0	0
VI	Nerve-related	21	3	23,065	375	1	1	1	1	0	0	1	0
VII	Eye and adnexa	24	-	43,182	-	2	-	1	-	2	-	1	-
VIII	Ear and mastoid process	5	-	7,317	-	0	-	0	-	0	-	0	-
IX	Circulatory	41	19	279,306	19,836	14	9	1	0	10	8	1	0
X	Respiratory	21	10	175,637	4,564	14	5	1	0	14	5	1	0
XI	Digestive	51	3	132,817	1,038	10	1	4	0	5	1	1	0
XII	Skin and subcutaneous tissue	11	1	12,273	29	2	0	1	0	0	0	0	0
XIII	Musculoskeletal	34	1	99,111	125	1	0	5	0	0	0	2	0
XIV	Genitourinary	54	2	78,577	552	2	0	5	0	0	0	0	0
XV	Pregnancy-related	6	1	3,745	1	1	0	0	0	0	0	0	0
XVIII	Other symptoms, signs and abnormal findings	35	3	87,254	831	10	2	0	0	7	1	0	0
XIX	Injury, poisoning and other external causes	38	1	41,073	79	4	0	0	0	0	0	0	0
XX	External causes	10	8	3,894	3,268	0	0	1	1	0	0	0	0
	Total	476	85	1,137,603	48,760	87	28	23	2	56	22	7	0