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. Author manuscript; available in PMC: 2022 Dec 14.
Published in final edited form as: Lancet Public Health. 2022 Dec;7(12):e1014–e1026. doi: 10.1016/S2468-2667(22)00227-4

Table 2. Adjusted HRs for incident risks of five major diseases associated with smoking, among urban and rural men.

Smoking category Lung cancer Ischaemic heart disease Ischaemic stroke Haemorrhagic stroke COPD
Number of events HR (95% CI) Number of events HR (95% CI) Number of events HR (95% CI) Number of events HR (95% CI) Number of events HR (95% CI)
Urban men
Never-regular smoker 242 1.00 (0.88, 1.14) 3,120 1.00 (0.96, 1.04) 3,593 1.00 (0.97, 1.03) 473 1.00 (0.91, 1.10) 463 1.00 (0.91, 1.10)
Ever-regular smoker 1,227 2.58 (2.24, 2.98) 7,220 1.27 (1.22, 1.33) 7,286 1.14 (1.09, 1.19) 996 1.14 (1.02, 1.28) 1,576 2.26 (2.02, 2.51)
   Ex-smoker (by choice) 134 1.48 (1.25, 1.76) 1,139 1.10 (1.03, 1.16) 1,201 1.01 (0.96, 1.07) 152 1.01 (0.86, 1.19) 205 1.40 (1.22, 1.61)
Regular smoker 1,093 2.87 (2.70, 3.06) 6,081 1.31 (1.28, 1.35) 6,085 1.17 (1.14, 1.20) 844 1.17 (1.09, 1.26) 1,371 2.50 (2.37, 2.64)
       Ex-smoker (ill health) 190 2.35 (2.03, 2.71) 1,288 1.55 (1.46, 1.63) 1,162 1.16 (1.10, 1.23) 180 1.37 (1.18, 1.58) 415 3.13 (2.84, 3.45)
       Current smoker 903 3.04 (2.83, 3.26) 4,793 1.26 (1.22, 1.30) 4,923 1.17 (1.13, 1.20) 664 1.12 (1.03, 1.22) 956 2.28 (2.13, 2.44)
Age began smoking (years)*
   25+ 306 2.23 (1.99, 2.49) 1,954 1.23 (1.18, 1.29) 2,020 1.09 (1.04, 1.14) 278 1.13 (1.01, 1.27) 436 1.95 (1.77, 2.14)
   18-24 595 3.14 (2.89, 3.41) 3,161 1.33 (1.28, 1.38) 3,141 1.18 (1.14, 1.23) 439 1.19 (1.08, 1.31) 669 2.67 (2.47, 2.88)
   <18 192 3.64 (3.15, 4.21) 966 1.55 (1.45, 1.65) 924 1.33 (1.25, 1.42) 127 1.19 (0.99, 1.42) 266 3.73 (3.30, 4.22)
No. smoked (cig/day)*
   <15 335 2.17 (1.94, 2.42) 2,280 1.20 (1.15, 1.25) 2,337 1.09 (1.05, 1.14) 316 1.12 (1.00, 1.25) 478 2.14 (1.95, 2.35)
   15-24 525 3.06 (2.81, 3.34) 2,722 1.33 (1.28, 1.38) 2,747 1.19 (1.15, 1.24) 387 1.18 (1.07, 1.30) 630 2.56 (2.37, 2.77)
   25+ 233 4.03 (3.54, 4.59) 1,079 1.65 (1.56, 1.76) 1,001 1.29 (1.21, 1.37) 141 1.26 (1.06, 1.49) 263 3.11 (2.75, 3.51)
Rural men
Never-regular smoker 258 1.00 (0.88, 1.13) 2,425 1.00 (0.96, 1.04) 2,612 1.00 (0.96, 1.04) 1,037 1.00 (0.94, 1.06) 1,421 1.00 (0.95, 1.05)
Ever-regular smoker 2,215 2.23 (1.96, 2.55) 9,668 1.19 (1.14, 1.25) 9,429 1.11 (1.06, 1.16) 3,649 0.99 (0.92, 1.06) 7,799 1.52 (1.44, 1.61)
   Ex-smoker (by choice) 137 1.56 (1.32, 1.84) 723 1.11 (1.03, 1.20) 738 0.99 (0.92, 1.07) 271 0.95 (0.85, 1.08) 470 1.14 (1.04, 1.25)
   Regular smoker 2,078 2.30 (2.20, 2.41) 8,945 1.20 (1.18, 1.23) 8,691 1.12 (1.09, 1.14) 3,378 0.99 (0.96, 1.03) 7,329 1.56 (1.52, 1.59)
      Ex-smoker (ill health) 219 1.97 (1.72, 2.25) 1,187 1.51 (1.42, 1.59) 1,160 1.31 (1.24, 1.39) 432 1.18 (1.08, 1.30) 1,218 2.25 (2.12, 2.38)
      Current smoker 1,859 2.35 (2.24, 2.47) 7,758 1.16 (1.14, 1.19) 7,531 1.09 (1.07, 1.12) 2,946 0.97 (0.93, 1.00) 6,111 1.46 (1.43, 1.50)
Age began smoking (years)*
   25+ 526 1.71 (1.57, 1.86) 2,824 1.09 (1.05, 1.14) 2,802 1.06 (1.02, 1.10) 1,151 0.94 (0.89, 1.00) 1,926 1.22 (1.17, 1.28)
   18-24 1,096 2.42 (2.28, 2.57) 4,459 1.22 (1.18, 1.26) 4,356 1.13 (1.09, 1.16) 1,612 0.99 (0.94, 1.04) 3,744 1.65 (1.60, 1.70)
   <18 456 3.13 (2.85, 3.43) 1,662 1.37 (1.31, 1.44) 1,533 1.21 (1.15, 1.27) 615 1.09 (1.01, 1.18) 1,659 1.97 (1.87, 2.07)
No. smoked (cig/day)*
   <15 524 1.70 (1.55, 1.85) 3,459 1.16 (1.12, 1.20) 3,531 1.08 (1.05, 1.12) 1,420 1.04 (0.99, 1.10) 2,234 1.43 (1.37, 1.49)
   15-24 994 2.40 (2.26, 2.56) 3,798 1.20 (1.16, 1.24) 3,614 1.12 (1.09, 1.16) 1,342 0.92 (0.88, 0.98) 3,313 1.61 (1.55, 1.67)
   25+ 560 3.27 (3.00, 3.57) 1,688 1.31 (1.25, 1.38) 1,546 1.21 (1.15, 1.28) 616 1.01 (0.93, 1.10) 1,782 1.68 (1.60, 1.76)

All analyses were stratified by study area and 5-year age-at-risk group and adjusted for education and alcohol drinking.

Only include those who had quit voluntarily (i.e. not due to ill health).

*

Include current smokers and ex-smokers who had quit due to ill health.