Table 1. Table summarizing the effects of the matrix-bound proteins on the different cellular processes, including cell adhesion, spreading, and proliferation, for the two cell types: PANC1 cell line and PAN092 cells on stiff or soft films with matrix-bound bFN, bBMP2 and bBMP4.
The ‘+’, ‘++’, “+++” and “++++” indicate an increasing level of positive effects, while “-” and “--” indicate a negative effect on the process. “=“ indicates that there is no effect on the process
| bFN | bBMP-2 | bBMP-4 | ||
|---|---|---|---|---|
| PANC-1 EDC30 | Adhesion | +++ | + dose-dependent | + dose-dependent |
| Spreading | = | = | = | |
| Proliferation | +++ | ++++ low dose | ++ dose-dependent | |
| = high dose | ||||
| PANC-1 EDC70 | Adhesion | ++ | = | = |
| Spreading | = | = | = | |
| Proliferation | +++ |
++++ low dose = high dose |
++ high dose | |
| + low dose | ||||
| PAN092 EDC30 | Adhesion | +++ |
+ low dose = high dose |
- dose-dependent |
| Spreading | + dose-dependent | = | = | |
| Proliferation | ++ | -- | = | |
| PAN092 EDC70 | Adhesion | +++ | = | = |
| Spreading | = | = | = | |
| Proliferation | + | ~+ | ~+ |