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. 2022 Sep 2;28(1):256–268. doi: 10.1038/s41380-022-01743-z

Table 1.

The pharmacology of precision. Please see [92] for details.

Neurotransmitter system Functional role Neuroanatomy
Cholinergic Encoding the precision of outcomes given hidden states: (c.f., Attention and expected uncertainty [218, 219]) Nucleus basalis of Meynert
Noradrenergic Encoding the precision of state transitions (c.f., Volatility and unexpected uncertainty [220]) Locus coeruleus
Dopaminergic Encoding the precision of beliefs about policies (c.f. Action selection [221]) Substantia nigra pars compacta, Ventral tegmental area