Extended Data Table 5.
Side effects by Hypothesised Drug/Strata Combinations. Proportions experiencing at least one side effect for each of the hypothesised drug/strata combinations.
| Hypothesis 1 | Pioglitazone | Sitagliptin |
| BMI>30kg/m2 | 238/277 (86%) | 217/278 (78%) |
| BMI<=30kg/m2 | 152/192 (79%) | 148/196 (76%) |
| Hypothesis 2 | Sitagliptin | Canagliflozin |
| eGFR 60-90 | 174/227 (77%) | 178/221 (81%) |
| eGFR>90 | 191/247 (77%) | 215/253 (85%) |