Skip to main content
. Author manuscript; available in PMC: 2023 Feb 22.
Published in final edited form as: Nat Med. 2022 Dec 7;29(2):376–383. doi: 10.1038/s41591-022-02120-7

Extended Data Table 5.

Side effects by Hypothesised Drug/Strata Combinations. Proportions experiencing at least one side effect for each of the hypothesised drug/strata combinations.

Hypothesis 1 Pioglitazone Sitagliptin
BMI>30kg/m2 238/277 (86%) 217/278 (78%)
BMI<=30kg/m2 152/192 (79%) 148/196 (76%)
Hypothesis 2 Sitagliptin Canagliflozin
eGFR 60-90 174/227 (77%) 178/221 (81%)
eGFR>90 191/247 (77%) 215/253 (85%)