. Author manuscript; available in PMC: 2023 Mar 4.

Published in final edited form as: Am J Psychiatry. 2015 Jun 18;172(12):1215–1223. doi: 10.1176/appi.ajp.2015.14101298

Table 2. Prediction of Transition to Subthreshold and Clinical Depression at 2-Year Follow-Up in Previously Healthy Adolescents From Baseline Activity in the Ventral Striatum and Left Middle Superior Frontal Gyrus.

Outcome and Baseline Adjustment	Left Ventral Striatum			Right Ventral Striatum			Left Middle Frontal Gyrus
Outcome and Baseline Adjustment	Odds Ratio	95% CI	p	Odds Ratio	95% CI	p	Odds Ratio	95% CI	p
Onset of subthreshold depression
Standard^a	0.81	0.69, 0.96	0.016	0.82	0.71, 0.95	0.007	0.87	0.68, 1.12	0.284
Symptoms at baseline	0.82	0.69, 0.96	0.016	0.82	0.72, 0.95	0.007	0.88	0.68, 1.12	0.297
Onset of clinical depression
Standard^a	0.80	0.58, 1.11	0.184	0.66	0.45, 0.97	0.037	0.71	0.53, 0.96	0.027
Symptoms at baseline	0.81	0.60, 1.10	0.180	0.68	0.47, 0.99	0.042	0.74	0.56, 0.98	0.035

Standard adjustment includes sex, age, handedness, and pubertal status. The robust cluster option was used for scanning site.