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. Author manuscript; available in PMC: 2023 Mar 13.
Published in final edited form as: Nat Rev Mol Cell Biol. 2021 Sep 30;23(2):93–106. doi: 10.1038/s41580-021-00417-y

Box 1 Figure.

Box 1 Figure

Structure of poly(A) RNA (purple) bound to the Pan2 exonuclease domain (pink) (PDB 6R9J)42. The poly(A) RNA forms an A-form like, single-stranded helix where the bases are stacked on top of each other.