Figure 2. Summary of Pharmacokinetics: (A) AUC and (B) Cmax versus Dose of AZD3965 at D-7.
Dose level of 20 mg includes data from AZD3965 20 mg OD and 10 mg BD dose cohorts (both received 20 mg on D-7) and dose level of 30 mg includes data from AZD3965 30 mg OD and 15 mg BD dose cohorts (both received 30 mg on D-7). Both panels show individual data per patient.
Abbreviations: AUC, area under the curve; Cmax, maximum plasma concentration; D=day.