TABLE 3.

Rejections and current significance level ${\alpha }_8$ of different algorithms using the results of the STAMPEDE trial, with the ordering as in Table 2.

	Hypotheses rejected			${\mathit{\alpha }}_{\mathbf{8}}$
Algorithm	$\alpha =0.025$	$\alpha =0.05$	$\alpha =0.1$	$\alpha =0.025$	$\alpha =0.05$	$\alpha =0.1$
Uncorrected	C, E, G	C, E, G	C, E, G	0.0250	0.0500	0.1000
Bonferroni	G	G	G	0.0013	0.0025	0.0050
ADDIS‐spending	G	G	G	0.0005	0.0011	0.0021
BH	C, G	C, G	C, E, G	–	–	–
ADDIS	–	G	G	0.0003	0.0016	0.0031
SAFFRON	G	C, G	C, E, G	0.0041	0.0165	0.0412
LORD	–	–	–	0.0001	0.0002	0.0003
LOND	G	G	G	0.0025	0.0050	0.0100
BatchBH	G	C, G	C, E, G	0.0019	0.0057	0.0151
BatchPRDS	G	C, G	C, E, G	0.0019	0.0057	0.0151
BatchStBH	C, G	C, E, G	C, E, G	0.0381	0.1015	0.1238