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. Author manuscript; available in PMC: 2023 Jun 14.
Published in final edited form as: Nat Med. 2022 Nov 10;28(11):2293–2300. doi: 10.1038/s41591-022-02055-z

Extended Data Fig. 7. Percentage of variance explained in impaired glucose tolerance and isolated impaired glucose tolerance top discriminatory protein levels by clinical, biochemical, anthropometric and lifestyle risk factors.

Extended Data Fig. 7

Linear mixed models were fitted for each of the 24 clinical, biochemical, anthropometric, genetic and lifestyle risk factor variables adjusting by age and sex to estimate the percentage of explained variance in plasma abundances of discriminatory proteins as well as for the principal component of the 65-IGT and 68-iIGT protein signatures. Cis and trans scores with missing values represent proteins for which no protein quantitative trait loci could be identified.