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. Author manuscript; available in PMC: 2023 Jun 15.
Published in final edited form as: Stat Med. 2021 Sep 29;40(29):6634–6650. doi: 10.1002/sim.9203

Figure 1.

Figure 1

Simulation study: simulation scenarios for simple and complex composite endpoints; each combination in the dashed boxes was repeated independently Nrep = 2 000 times. x, randomized treatment; λ123, three-way interaction between the components in the log-linear model