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. Author manuscript; available in PMC: 2023 Jun 15.
Published in final edited form as: Stat Med. 2021 Sep 29;40(29):6634–6650. doi: 10.1002/sim.9203

Figure 5.

Figure 5

TOPPS reanalysis: difference in proportions of participants who had bleeding events between the two treatment arms under different methods for handling missing bleeding events. MIC-trt 1, MI performed by mi impute chained, imputation of each block is conditional on all other blocks and stratified by randomized treatment; MIC-trt 2, MI performed by ice, imputation of each block is conditional on all other blocks and stratified by randomized treatment; MIC-trt 3, MI performed by mi impute chained, imputation of each block is conditional on two adjacent blocks and stratified by randomized treatment