Table 1. Simulation study: all possible combinations of the components for constructing the simple and complex composite endpoints, and associated linear predictors in the log-linear model for the combinations of components.
| Combination c | Z 1 | Z 2 | Z 3 | y simple | y complex | Linear predictor LPc for log (μc) |
|---|---|---|---|---|---|---|
| 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | 0 | 0 | 1 | 1 | 0 | λ 3 |
| 3 | 0 | 1 | 0 | 1 | 0 | λ 2 |
| 4 | 0 | 1 | 1 | 1 | 0 | λ2 + λ3 + λ23 |
| 5 | 1 | 0 | 0 | 1 | 0 | λ 1 |
| 6 | 1 | 0 | 1 | 1 | 1 | λ1 + λ3 + λ13 |
| 7 | 1 | 1 | 0 | 1 | 1 | λ1 + λ2 + λ12 |
| 8 | 1 | 1 | 1 | 1 | 1 | λ1 + λ2 + λ3 + λ12 + λ23 + λ13 + λ123 |