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. 2023 Apr 13;14:100196. doi: 10.1016/j.lansea.2023.100196

Table 1.

Maternal and infant characteristics and their association with maternal cortisol levels (n = 230).

Variables Categories Cortisol levels
p-value
Low (≤17.66 μg/L) (n = 116) High (>17.66 μg/L) (n = 114)
Maternal age (years) Continuous (mean & SD) 24.93 (±4.47) 23.51 (±3.8) 0.012
Maternal age (years) 18–25 (Ref) 11 (4.8) 07 (3)
26–30 36 (15.7) 25 (10.8) 0.221
>30 69 (30) 82 (35.7) 0.08
Gravida 1 (Ref) 36 (15.7) 49 (21.3)
2 50 (21.7) 46 (20) 0.037
≥3 30 (13) 19 (8.3) 0.296
Parity Nullipara (Ref) 41 (17.8) 55 (23.9)
Primi 62 (27) 52 (22.6) 0.075
Multi 13 (5.7) 07 (3) 0.38
BMI Normal (18.5–22.9) (Ref) 36 (15.7) 41 (17.8)
Underweight (<18.5) 05 (2.2) 09 (3.9) 0.223
Overweight (23–24.9) 19 (8.3) 20 (8.7) 0.162
Obese (≥25) 56 (24.3) 44 (19.1) 0.44
spousal smoking cigarette No (Ref) 70 (31.3) 70 (31.3) 0.863
Yes 41 (18.3) 43 (19.2)
Spousal alcohol habit No (Ref) 91 (40.6) 100 (44.6) 0.172
Yes 20 (8.9) 13 (5.8)
History of abortion No (Ref) 90 (39.1) 95 (41.3) 0.273
Yes 26 (11.3) 19 (8.3)
GDM No (Ref) 90 (39.1) 96 (41.7) 0.203
Yes 26 (11.3) 18 (7.8)
HYP No 106 (46.1) 108 (47) 0.322
Yes 10 (4.3) 6 (2.6)
Respondent's sum of skin fold <90th percentile (Ref) 107 (46.5) 100 (43.5) 0.257
≥90th percentile 9 (3.9) 14 (6.1)
Depressive symptoms No (0–12) (Ref) 97 (42.2) 91 (39.6) 0.457
Yes (≥13) 19 (8.3) 23 (10)
Social support ≥24 (Ref) 55 (23.9) 53 (23.1) 0.889
<24 61 (26.5) 61 (26.5)
GA at delivery <37 weeks 07 (3) 08 (3.5) 0.763
≥37 weeks (Ref) 109 (47.4) 106 (46.1)
Infant characteristics
Infant gender Female (Ref) 47 (20.4) 66 (28.7)
Male 69 (30) 48 (20.9) 0.008
Low birth weight (<2.5 kg) No (Ref) 76 (33) 88 (38.3)
Yes 40 (17.4) 26 (11.3) 0.05
SGA No (Ref) 63 (27.5) 63 (27.5)
Yes 53 (23.1) 50 (21.8) 0.826
WLZ (<10th percentile) No (Ref) 86 (37.6) 96 (41.9)
Yes 30 (13.1) 17 (7.4) 0.043
HC (<10th percentile) No (Ref) 102 (44.5) 103 (45)
Yes 14 (6.1) 10 (4.4) 0.426
SSF (<10th percentile) No (Ref) 103 (44.8) 104 (45.2)
Yes 13 (5.7) 10 (4.3) 0.539

The bold values are the p-values obtained for the listed variables. Maternal factors such as maternal age, gravida and infant characteristics such as gender, weight for length are the factors significantly differ between the cortisol groups.

GA-gestational age, BMI-Body mass index, GDM-pregnancy gestational diabetes mellitus, HYP-pregnancy hypertension, SGA-Small for gestational age, WLZ-weight for length z-score, HC-head circumference, SSF-sum of skinfold thickness.