Fig. 2. Distinct cytoarchitectonic and resting-state network profiles for synergy-dominated and redundancy-dominated regions.

(a) Regional redundancy-to-synergy gradient values for each canonical resting-state network, based on the definition of Yeo et al. (2011) ²². DMN, default mode network. SOM, somatomotor network. VIS, visual network. SAL, salience/ventral attention network; DAN, dorsal attention network. FPN, fronto-parietal executive control network. LIM, limbic network. SUB, subcortical network. (b) Regional redundancy-to-synergy gradient values for each of seven cytoarchitectonic classes (the five canonical classes identified by Von Economo, plus limbic and insular cortices), for 308 cortical ROIs of equal size (500 mm2), obtained from subdivisions of the Desikan-Killiany cortical parcellation ²¹. For both panels, each colored circle represents one brain region; panel (a), n=232 regions divided into 8 resting-state networks; panel (b), n=308 regions divided into 7 cytoarchitectonic classes. Each violin plot shows the distribution of brain regions assigned to the subnetwork or cytoarchitectonic class indicated on the x-axis (for each panel, each region is assigned exactly once). White circle: median; central line: mean; box limits, upper and lower quartiles; whiskers, 1.5x inter-quartile range; * p < 0.05; ** p < 0.01; *** p < 0.001 from one-sample non-parametric permutation t-test (two-sided), corrected for multiple comparisons using the False Discovery Rate. Full statistical results are shown in Supplementary Table 1 (Yeo RSN) and Supplementary Table 2 (Von Economo).