Table 1. Characteristics of contributing studies included in individual participant data meta-analysis.

Authors	Publication Year	Country	n (total)	Adults/children	Population	Follow-up years (median (IQR))	TB cases	Loss to follow-up	Included in prediction modeling	NOSa
Abubakar et al.9	2018	UK	10,045	Adults	Contacts & migrants	4.7 (3.7–5.5)	147	10 (0.1%)	Yes	7/7
Aichelburg et al.26	2009	Austria	830	Adults	People with HIV	1.2 (0.7–1.4)	11	25 (3%)	Yes	7/7
Altet et al.17	2015	Spain	1,339	Adults & children	Contacts	4(4–4)	95	0 (0%)	Yes	7/7
Diel et al.18	2011	Germany	1,414	Adults & children	Contacts	3.5 (2.5–4.2)	19	381 (26.9%)	Yes	7/7
Dobler & Marks19	2013	Australia	12,212	Adults & children	Contacts	4.2 (2–6.9)	94	351 (2.9%)	Nob	7/7
Doyle et al.27	2014	Australia	919	Adults	People with HIV	2.9 (1.7–3.6)	2	47 (5.1%)	Yes	7/7
Erkens et al.32	2016	Netherlands	14,241	Adults & children	Mixed population screening	5.5 (3–7.4)	134	NA	Nob	6/6
Geis et al.20	2013	Germany	1,283	Adults & children	Contacts	0.8 (0.4–1.1)	33	62 (4.8%)	Yes	6/6
Gupta et al.25	2020	UK	623	Adults	Contacts	1.9 (1.6–2.2)	13	0 (0%)	Yes	7/7
Haldar et al.21	2013	UK	1,411	Adults & children	Contacts	1.9 (1.3–2.4)	37	30 (2.1%)	Yes	7/7
Lange et al.28	2012	Germany	456	Adults	Immunocompromised	2.8 (2–3.1)	1	42 (9.2%)	Yes	7/7
Munoz et al.30	2015	Spain	76	Adults	Transplant recipients	4.3 (3.6–4.8)	2	0 (0%)	Yes	7/7
Roth et al.31	2017	Canada	22,949	Adults & children	Mixed population screening	3 (1.8–4.3)	58	NA	Subsetb	6/6
Sester et al.29	2014	Multiple European countries	1,464	Adults	Immunocompromised	2.7 (1.5–3.5)	11	7 (0.5%)	Yes	7/7
Sloot et al.22	2014	Netherlands	5,895	Adults & children	Contacts	5.9 (3.6–7.7)	81	NA	Yes	7/7
Yoshiyama et al.23	2015	Japan	625	Adults & children	Contacts	1.8 (1.4–2)	12	0 (0%)	Yes	6/7
Zellweger et al.24	2015	Multiple European countries	5,237	Adults & children	Contacts	2.6 (1.9–3.5)	55	1339 (25.6%)	Yes	7/7
Zenner et al.33	2017	UK	1,341	Adults	Migrants	3.7 (3–4.8)	21	NA	Nob	7/7
Total			82,360			3.7 (2.1–5.3)	826	2294 (2.8%)

^aModified version of the Newcastle-Ottawa Scale for cohort studies.

^bNot included in prediction modeling owing to lack of data on proximity or infectiousness of index cases¹⁹ or absent quantitative LTBI test data^32,33. A subset of the data set was included in the prediction model for the Roth et al. study³¹; contacts and migrants were excluded owing to no data being available on country of birth or infectiousness of index cases, respectively. Additional study characteristics are shown in Supplementary Table 1.