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. Author manuscript; available in PMC: 2023 Jul 27.
Published in final edited form as: Circulation. 2017 Jan 25;135(13):1194–1210. doi: 10.1161/CIRCULATIONAHA.116.025778

Table 2. Standardised Hospitalisation Ratio, Relative Risk, Absolute Excess Risk and Excess Hospitalisation Ratio of any and specific cerebrovascular events according to attained age.

Cerebrovascular Event Attained Age (years) O SHR (95% CI) RR (95% CI)* AER (95% CI) EHR (95% CI)*
Any CV Event (ICD10: I60-I68) 20-44 549 2.0 (1.9,2.2) 1.0 Ref 3.7 (3.1,4.3) 1.0 Ref
45-49 433 1.5 (1.3,1.6) 0.9 (0.7,1.0) 3.7 (2.6,4.7) 1.6 (1.2,2.2)
50-54 512 1.5 (1.4,1.7) 0.9 (0.8,1.1) 6.1 (4.5,7.6) 2.1 (1.4,2.9)
54-59 455 1.3 (1.2,1.4) 0.9 (0.7,1.0) 5.4 (3.3,7.4) 2.4 (1.5,3.6)
60+ 833 1.1 (1.0,1.2) 0.8 (0.7,1.0) 3.5 (0.9,6.2) 2.4 (1.5,4.1)
P-trend <0.001 0.086 0.122 <0.001
Cerebral Haemorrhage(ICD10: I61-I62) 20-44 193 3.6 (3.1,4.2) 1.0 Ref 1.8 (1.5,2.2) 1.0 Ref
45-49 110 2.2 (1.8,2.6) 0.7 (0.6,0.9) 1.6 (1.0,2.1) 1.1 (0.7,1.6)
50-54 106 1.9 (1.6,2.3) 0.7 (0.5,1.0) 1.7 (1.0,2.4) 1.2 (0.7,2.0)
54-59 92 1.7 (1.4,2.1) 0.7 (0.5,1.0) 1.9 (1.0,2.8) 1.1 (0.6,2.2)
60+ 117 1.2 (1.0,1.4) 0.6 (0.4,0.8) 0.7 (-0.2,1.7) 1.0 (0.4,2.3)
P-trend <0.001 0.016 0.137 0.610
Cerebral infarction (ICD10: I63, I65-66) 20-44 197 2.2 (1.9,2.5) 1.0 Ref 1.4 (1.0,1.8) 1.0 Ref
45-49 191 1.8 (1.5,2.0) 0.9 (0.7,1.1) 2.2 (1.5,2.9) 2.7 (1.8,4.1)
50-54 242 1.8 (1.6,2.0) 0.9 (0.7,1.2) 3.7 (2.7,4.8) 3.7 (2.3,6.0)
54-59 238 1.6 (1.4,1.8) 0.8 (0.6,1.1) 4.2 (2.7,5.7) 5.1 (2.9,8.8)
60+ 428 1.1 (1.0,1.3) 0.7 (0.5,0.9) 2.5 (0.6,4.4) 5.6 (2.9,10.8)
P-trend <0.001 0.018 <0.001 <0.001
Other CV event (ICD10: I64, I67-I68) 20-44 161 1.8 (1.6,2.1) 1.0 Ref 1.0 (0.6,1.3) 1.0 Ref
45-49 160 1.6 (1.3,1.8) 1.0 (0.8,1.3) 1.5 (0.8,2.2) 3.0 (1.9,4.9)
50-54 207 1.6 (1.4,1.9) 1.1 (0.9,1.4) 2.8 (1.8,3.8) 4.4 (2.6,7.4)
54-59 184 1.3 (1.2,1.6) 1.0 (0.7,1.3) 2.3 (1.0,3.6) 4.6 (2.5,8.7)
60+ 402 1.1 (1.0,1.3) 0.9 (0.7,1.3) 2.3 (0.5,4.2) 6.4 (3.1,12.9)
P-trend <0.001 0.605 <0.001 <0.001

Abbreviations: CV=cerebrovascular; ICD= International classification of disease; O= observed; SHR=standardised hospitalisation ratio; AER=absolute excess risk; CI=confidence interval; RR=relative risk; EHR=excess hospitalisation ratio; ref= reference level

*

Multivariable models and p-values are adjusted for cancer diagnosis, sex, age at cancer diagnosis, decade of cancer diagnosis and attained age