Table 5. SHR, AER, RR and EHR of any cerebrovascular event among survivors of leukaemia by , type of leukaemia, sex, age at diagnosis, decade of diagnosis and attained age.
O | SHR (95%CI) | RR (95%CI) | AER (95%CI) | EHR (95%CI) | |
---|---|---|---|---|---|
All Leukaemia | 70 | 2.5 (1.9,3.1) | 10.2 (6.2,14.2) | ||
Type of Leukaemia | |||||
Acute Lymphoblastic | 18 | 3.7 (2.2,5.9) | 1.0 Ref | 12.4 (4.6,20.3) | 1.0 Ref |
Acute Myeloid | 16 | 1.7 (1.0,2.8) | 0.6 (0.3,1.1) | 4.5 (-0.8,9.7) | 0.3 (0.1,1.7) |
Chronic Myeloid | 13 | 2.9 (1.6,5.0) | 0.9 (0.4,2.0) | 12.3 (2.1,22.5) | 1.1 (0.3,3.8) |
Other | 23 | 2.3 (1.5,3.5) | 0.9 (0.4,1.9) | 15.9 (4.5,27.3) | 1.0 (0.3,3.5) |
p-heterogeneity | 0.13 | 0.297 | 0.15 | 0.322 | |
Sex | |||||
Male | 47 | 2.7 (2.0,3.6) | 1.0 Ref | 13.0 (7.1,18.9) | 1.0 Ref |
Female | 23 | 2.1 (1.3,3.1) | 0.8 (0.5,1.4) | 6.6 (1.4,11.9) | 0.5 (0.2,1.3) |
p-heterogeneity | 0.29 | 0.409 | 0.262 | 0.258 | |
Age at FPN Diagnosis (years) | |||||
15-19 | 14 | 5.1 (2.8,8.6) | 1.0 Ref | 12.0 (4.2,19.9) | 1.0 Ref |
20-24 | 6 | 2.2 (0.8,4.7) | 0.4 (0.2,1.1) | 4.7 (-2.3,11.8) | 0.4 (0.1,1.8) |
25-29 | 10 | 2.4 (1.2,4.4) | 0.4 (0.2,1.0) | 8.1 (-0.5,16.8) | 0.4 (0.1,1.8) |
30-34 | 22 | 3.0 (1.9,4.5) | 0.5 (0.2,1.2) | 17.4 (6.4,28.4) | 0.6 (0.1,2.7) |
35-39 | 18 | 1.6 (0.9,2.5) | 0.2 (0.1,0.7) | 7.3 (-2.0,16.6) | 0.2 (0.0,1.3) |
p-trend | 0.007 | 0.017 | 0.696 | 0.15 | |
Decade of FPN Diagnosis | |||||
1971-1979 | 13 | 2.3 (1.2,3.9) | 1.0 Ref | 21.7 (0.5,42.9) | 1.0 Ref |
1980-1989 | 23 | 2.3 (1.4,3.4) | 1.2 (0.5,2.9) | 11.0 (3.0,19.0) | 1.0 (0.2,4.5) |
1990-2006 | 34 | 2.7 (1.9,3.7) | 1.7 (0.6,4.7) | 8.3 (3.9,12.8) | 1.1 (0.2,5.9) |
p-trend | 0.527 | 0.162 | 0.116 | 0.775 | |
Attained Age (years) | |||||
20-44 | 22 | 2.7 (1.7,4.2) | 1.0 Ref | 5.5 (1.9,9.1) | 1.0 Ref |
44-49 | 19 | 3.1 (1.9,4.9) | 1.6 (0.8,3.3) | 17.5 (5.9,29.1) | 5.0 (1.3,18.9) |
50-54 | 14 | 2.6 (1.4,4.4) | 1.6 (0.7,3.5) | 20.4 (3.1,37.8) | 6.0 (1.2,30.8) |
55+ | 15 | 1.6 (0.9,2.7) | 1.3 (0.5,3.6) | 16.3 (-4.7,37.4) | 7.9 (1.1,55.7) |
p-trend | 0.142 | 0.429 | 0.014 | 0.01 |
Abbreviations: O= observed; SHR=standardised hospitalisation ratio; AER=absolute excess risk; CI=confidence interval; RR=relative risk; EHR=excess hospitalisation ratio.