. Author manuscript; available in PMC: 2023 Jul 31.

Published in final edited form as: Eur Heart J Acute Cardiovasc Care. 2017 Mar 20;7(2):166–175. doi: 10.1177/2048872617700873

Table 1. Study Characteristics.

Authors	Number patients	Type study	Location	Year Published	Type ACS	Frailty Measure	Age	Prevalence (Frailty)	Prevalence (pre-frailty)	Outcome
Ekerstad et al. ¹⁶	307	Observational Cohort (Three Centres)	Sweden	2011	NSTEMI	CFS (Rockwood)	>75	48.5%	not defined	All-cause mortality
Ekerstad et al. ¹⁷	307	Observational Cohort (Three Centres)	Sweden	2013	NSTEMI	CFS (Rockwood)	>75	48.5%	not defined	All-cause mortality
Graham et al.¹⁸	183	Prospective Cohort (Single Centre)	Canada	2013	ACS	Edmonton	>65	30.0%	36.0%	All-cause mortality
Kang et al.¹⁹	352	Prospective Cohort (Single Centre)	China	2015	ACS	CFS (Rockwood)	>65	43.2%	not defined	All-cause mortality
Lisiak et al.²⁰	91	Prospective Cohort (Single Centre)	Poland	2016	ACS	Tilburg Frailty Indicator	>65	82.4%	not defined	Quality of life
Matsuwaza et al.²¹	472	Prospective Cohort (Single Centre)	Japan	2013	STEMI	Gait speed	Mean 63.1 (SD 11.8)	33.5%	not defined	All-cause mortality and recurrent cardiac events
Myers et al.²²	1521	Observational Cohort (Eight Centres)	Israel	2014	post MI	CFS (Rockwood)	Mean 55 (SD 7)	5.1%	34.7%	All-cause mortality
Salinas et al.²³	202	Observational Cohort (Four Centers)	Spain	2016	ACS	SHARE-FI	>75	35.1%	36.6%	All-cause mortality and MACE
Sanchis et al.²⁴	342	Prospective Cohort (Single Centre)	Spain	2014	ACS	Fried and Green	>65	47.0%	not defined	All-cause mortality
White et al.²⁵	4996	Sub study of TRILOGY	Multi Centre	2015	ACS	Fried	>65	4.7%	23.0%	Cardiovascular death, MI or stroke

Abbreviations; Ml (myocardia infarction); ACS (Acute Coronary Syndrome); NSTEMI (Non ST elevation myocardial infarction); STEMI (ST elevation myocardial infarction); CFS (Clinical Frailty Scale); MACE (major adverse cardiovascular events); SHARE-FI (Survey of Health, Ageing and Retirement in Europe – Frailty Index).