Table 2.
Adjusted risk of mortality for older people with frailty following acute coronary syndromes and percutaneous coronary intervention. For all outcomes, the comparator is older people defined as fit.
| Study | Frailty prevalence (%) | Study Population | Follow-up | Adjusted risk of all-cause mortality† | Adjusted cardiovascular mortality |
|---|---|---|---|---|---|
| Salinas et al.23 | 35.1% | ACS | In-hospital | OR 12.1 (95% CI 1.4-103) | Not defined |
| Ekerstad et al.16 | 48.5% | NSTEMI | 30 days | OR 2.17 (95% CI 1.28-3.67) | Not defined |
| Kang et al.19 | 43.2% | ACS | 4 months | HR 5.39 (95% CI 1,48-19.69) | Not defined |
| White et al.25 | 4.7% | ACS | 17 months | HR 1.54 (95% CI 1.13-2.08) | HR 1.41 (95% CI 1.00-1.99) |
| Sanchis et al.24 | 47.0% | ACS | 25 months | HR 3.4 (95% CI 1.8-6.2) | Not defined |
| Ekerstad et al.17 | 48.5% | NSTEMI | 1 year | HR 4.3 (95% CI 2.4-7.8) | Not defined |
| Graham et al.18 | 30.0% | ACS | 1 year | HR 3.49 (95% CI 1.08-7.61) | Not defined |
| Matsuwaza et al.21 | 33% | STEMI | 5.5 years | For increasing 0.1m/s gait speed HR 0.71 (95% CI 0.62-0.82) | For increasing 0.1m/s gait speed HR 0.65 (95% CI 0.55-0.81) |
| Myers et al.22 | 5.1% | MI | 13 years | HR 2.02 (95% CI 1.46-2.79) | 2.38 (95% CI 1.49-3.82) |
15
Abbreviations: MI (myocardial infarction); ACS (Acute Coronary Syndrome); NSTEMI (Non ST elevation myocardial infarction); STEMI (ST elevation myocardial infarction); OR, odds ratio; HR, hazard ratio; CI, confidence interval.
†
Adjustment was performed for age, sex, gender and clinical variables. Myers et al. also adjusted for socioeconomic status