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. Author manuscript; available in PMC: 2023 Jul 28.
Published in final edited form as: ACS Infect Dis. 2022 Jan 17;8(2):296–309. doi: 10.1021/acsinfecdis.1c00432

Scheme 1. Purine Biosynthetic Pathway, the Pathway Transforms PRPP (Phosphoribosyl Pyrophosphate) into IMP (Inosine Monophosphate) in 10 Biosynthetic Stepsa.

Scheme 1

aSAICAR synthetase (PurC) catalyzes seventh step in the biosynthetic pathway which transforms CAIR (carboxyaminoimidazole ribonucleotide) into SAICAIR (succinylaminoimidazole carboxyamide ribonucleotide) using ATP and L-aspartate.