Total glycoprotein-binding IgG responses at each measured timepoint are shown for group 1 (low dose, A), group 2 (middle dose, B), and group 3 (high dose, C). Arrowheads indicate administration of Rabipur (an inactivated rabies vaccine), with samples having been collected before Rabipur administration on applicable days. Each datapoint represents an individual volunteer, with lines connecting datapoints from an individual. Endpoint titres of glycoprotein-binding immunoglobulin isotypes and subclasses at day 28 after administration of ChAdOx2 RabG are shown (D). Each datapoint represents an individual volunteer.