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. Author manuscript; available in PMC: 2023 Jul 31.
Published in final edited form as: Nature. 2021 Aug 18;597(7876):410–414. doi: 10.1038/s41586-021-03830-7

Extended Data Figure 2. Sympathetic nervous system in the GAT and ILC2 function.

Extended Data Figure 2

a, GAT. Red: sympathetic nerve fibres (TH). Green: endothelial cells (CD31). Scale bar: 300μm. b, GAT ILC2-derived Met-Enk after 6-OHDA administration. n=5. c, CD4 T cells and TH positive CD4 T cells after 6-OHDA administration. n=4. d,e, Distance covered by mice in the open field test n=3. Scale bar=10cm. f, GAT ILC2-derived Met-Enk after Clenbuterol administration. n=5. g, Heatmap of Adrb1, Adrb2, and Adrb3, read counts (FPKM) on ILC2s, n=4. h, GAT ILC2 after CNO administration. R26/3Dfl n=4, R26Th n=4, and R26/3DTh n=5. i, Heatmap of Adrb1, Adrb2, and Adrb3, read counts (TPM) on MSCs, n=4. j, Gdnf expression after in vitro stimulation of MSCs, n=3. Data are representative of 3 independent experiments. n represents biologically independent animals. Data are presented as mean values and error bars: SEM. Two-tailed unpaired Welch's t-test. *P<0.05; ***P<0.005.