Table 1.
List of mouse genes which have been shown to affect clinical outcome and/or mortality following infection with WNV, DENV, ZIKV, YFV and JEV. Details of supporting studies are given in Table 2.
| Gene (synonym) | WNV | DENV | ZIKV | YFV | JEV |
|---|---|---|---|---|---|
| Atg16l1 | X | ||||
| Ccr2 | X | X | |||
| Ccr4 | X | ||||
| Ccr7 | X | ||||
| Clec5a | X | ||||
| Cxcl10 | X | X | |||
| Cxcr3 | X | X | |||
| Ddx58 (RIG-I) | X | ||||
| Dhx58 (LGP2) | X | ||||
| Ifih1 (MDA5) | X | ||||
| Ifi27l2a | X | ||||
| Ifit2 | X | ||||
| Ifitm3 | X | ||||
| Ifna | X | ||||
| Ifnb | X | ||||
| Ifng | X | ||||
| Ifnar1 | X | X | X | X | |
| Ifngr1 | X | X | X | X | |
| Ifnlr1 | X | X | X | ||
| Il10 | X | ||||
| Il12a | X | ||||
| Il12b | X | ||||
| Il23a | X | ||||
| Irf1 | X | X | |||
| Irf3 | X | X | X | ||
| Irf5 | X | X | X | ||
| Irf7 | X | X | X | ||
| Isg15 | X | ||||
| Mavs (IPS-1) | X | ||||
| Mb21d1 (cGas) | X | ||||
| Myd88 | X | ||||
| Oas1b | X | ||||
| Rag1 | X | X | |||
| Rag2 | X | ||||
| Rnasel | X | ||||
| Rsad2 | X | ||||
| Sema7a | X | ||||
| Stat1 | X | X | X | X | |
| Stat2 | X | X | |||
| Tlr3 | X | ||||
| Tlr7 | X | ||||
| Tnfrsf9 | X |