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Model-predicted dynamics of protective antibody and egg output during and after MDA for schistosomiasis. Treatment applied at yearly intervals for 5 years (asterisks) to a large population of school-aged children (6-15 years old) with 75% coverage. (a) Antibody levels. (b) Egg output. Figures compare results when MDA reduces transmission by 0, 50 or 100%. This model assumes a relatively short-lived memory response and a worm life span of 6.5 years. Full details are given in ref 12.
