A. An inversion generated through ectopic recombination affects the
transcription level of two genes by changing their positions in the genome relative to a
promoter. B. An inversion generated through staggered breaks generates a new
chimeric gene, while avoiding the loss of the donor genes because of duplication. Grey and
black arrows represent genes, with orientation indicated via arrow direction; a, b, c, d
represent single strand breaks, resulting in two staggered breaks.