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. Author manuscript; available in PMC: 2023 Aug 14.
Published in final edited form as: Muscle Nerve. 2021 Dec 6;65(5):581–585. doi: 10.1002/mus.27465

Table 1. Results of patients with positive genetics for periodic paralysis and/or positive long exercise test.

Variables Genetics positive LET positive Genetics positive LET negative Genetics negative LET positive p value Statistical test
Patients n = 32 n = 13 n = 22 N/A N/A
Age in years 36.6±14.2 (15-64) 44.4±15.4 (18-77) 36.4±12.8 (17-63) 0.197 ANOVA
Gender M/F (M:F ratio) 26/6 (4.3 : 1) 8/5 (1.6 : 1) 21/1 (21 : 1) 0.040 Fisher
No of patients on PP medication (%) 20 (62.5%) 3 (23.1%) 2 (9.1%)
Largest CMAP in mV 8.1±1.8*
(4.2-11.6)
9.1±1.8
(4.4-12.8)
10.5±2.1*
(6.0-15.2)
<0.001 ANOVA
Increment in % 28.4±26.4
(-11-119)
11.8±15.1
(-13-48)
28.1±14.9
(4-58)
0.017 Kruskal-Wallis
Decrement from peak in % 55.0±11.6
(33-80)
28.7±6.4
(15-39)
51.3±8.4
(42-68)
N/A N/A
Decrement from baseline in % 41.8±19.1
(-12-81)
2O.1±11.2
(0-38)
37.9±12.2
(12-57)
N/A N/A
Time to 40% decrement in minutes 21.4±13.0
(4-54)
N/A 28.7±12.6
(3-46)
0.051 t

Continuous quantitative data were plotted as mean ± standard deviation (range).

*

Groups with statistically significant differences

Statistical analysis was not performed as group allocation was according to peak decrement.

4/32 patients incorporated after SET calculations could not be included as a 40% decrement was not achieved during LET.

PP: periodic paralysis; CMAP: compound muscle action potential; F: female; LET: long exercise test; M: male; N/A: not applicable