Table 1. Results of patients with positive genetics for periodic paralysis and/or positive long exercise test.
Variables | Genetics positive LET positive | Genetics positive LET negative | Genetics negative LET positive | p value | Statistical test |
---|---|---|---|---|---|
Patients | n = 32 | n = 13 | n = 22 | N/A | N/A |
Age in years | 36.6±14.2 (15-64) | 44.4±15.4 (18-77) | 36.4±12.8 (17-63) | 0.197 | ANOVA |
Gender M/F (M:F ratio) | 26/6 (4.3 : 1) | 8/5 (1.6 : 1) | 21/1 (21 : 1) | 0.040 | Fisher |
No of patients on PP medication (%) | 20 (62.5%) | 3 (23.1%) | 2 (9.1%) | ||
Largest CMAP in mV | 8.1±1.8* (4.2-11.6) |
9.1±1.8 (4.4-12.8) |
10.5±2.1* (6.0-15.2) |
<0.001 | ANOVA |
Increment in % | 28.4±26.4 (-11-119) |
11.8±15.1 (-13-48) |
28.1±14.9 (4-58) |
0.017 | Kruskal-Wallis |
Decrement from peak in % | 55.0±11.6 (33-80) |
28.7±6.4 (15-39) |
51.3±8.4 (42-68) |
N/A† | N/A |
Decrement from baseline in % | 41.8±19.1 (-12-81) |
2O.1±11.2 (0-38) |
37.9±12.2 (12-57) |
N/A† | N/A |
Time to 40% decrement in minutes | 21.4±13.0 ‡ (4-54) |
N/A | 28.7±12.6 (3-46) |
0.051 | t |
Continuous quantitative data were plotted as mean ± standard deviation (range).
Groups with statistically significant differences
Statistical analysis was not performed as group allocation was according to peak decrement.
4/32 patients incorporated after SET calculations could not be included as a 40% decrement was not achieved during LET.
PP: periodic paralysis; CMAP: compound muscle action potential; F: female; LET: long exercise test; M: male; N/A: not applicable