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. Author manuscript; available in PMC: 2023 Aug 14.
Published in final edited form as: Nat Immunol. 2021 Sep 23;22(10):1231–1244. doi: 10.1038/s41590-021-01029-6

Extended Data Fig. 5. Comparative gene expression of ILCP from reporter, RKO and DKO mice.

Extended Data Fig. 5

a, Violin plots for enrichment score of gene modules of top 100 differentially expressed genes from reporter ILC2 within ILC2 cluster in indicated mouse strains. Statistical significance was calculated using two-sided Wilcoxon test with Bonferroni correction, all ns. (b) Eomes expression in DKO mice projected on UMAP. (c) Expression of selected ILCP-associated genes in cells from ILCP cluster in indicated mouse strains. (d) Expression of selected proteins on UMAP projection analysed by CITE-Seq. (e) Violin plot for Mki67 transcripts among ILCP in all mouse strains, legend see in (c). (f) Representative flow cytometry of Ki67 expression in LinLD- CD45+CD127+ROR□t-PD1hiPLZFhi cells from E15.5 SI (reporter n=6, RKO n=4, DKO n=6 from 2 independent experiments). Quantification as mean ± SEM with Kruskal-Wallis significance and Dunn’s correction. Detailed statistics are available in source data.