Cytokine concentrations of A) IL-4, B) IL-5, and C) IL-13 in the supernatant of human primary CD4+ T cells after 48 h of activation and subsequent transfection with Tf-Mel-PEI polyplexes containing 25 pmol of a 1:1 mixture of siRNA sequences GATA3_8 and GATA3_9. Control cells were left untreated (blank) or transfected with respective polyplexes containing scrambled siRNA as negative control (NC). (Data points indicate mean ± SD, n = 3; One-way ANOVA, *, p < 0.05; **, p < 0.01; ***, p < 0.005).