Table 2. The association of hypertension with the risk of cardio-cerebrovascular events in Harbin.

Outcomes	Groups	Cases/N	Model 1	Model 2	Model 3	Model 4
Cardio-cerebrovascular	Non-hypertension	4969/29202	1.000(ref.)	1.000(ref.)	1.000(ref.)	1.000(ref.)
disease	Hypertension	2925/9387	1.474(1.405,1.546)	1.350(1.285-1.419)	1.357(1.291-1.426)	1.347(1.281-1.415)
	P-value		<0.001	<0.001	<0.001	<0.001
CVD	Non-hypertension	4929/29202	1.000(ref.)	1.000(ref.)	1.000(ref.)	1.000(ref.)
	Hypertension	2909/9387	1.476(1.407-1.548)	1.352(1.287-1.421)	1.358(1.292-1.427)	1.347(1.282-1.416)
	P-value		<0.001	<0.001	<0.001	<0.001
MACE	Non-hypertension	2156/29202	1.000(ref.)	1.000(ref.)	1.000(ref.)	1.000(ref.)
	Hypertension	1764/9387	1.850(1.733-1.976)	1.690(1.578-1.809)	1.688(1.577-1.807)	1.670(1.560-1.788)
	P-value		<0.001	<0.001	<0.001	<0.001
Stroke	Non-hypertension	2116/29202	1.000(ref.)	1.000(ref.)	1.000(ref.)	1.000(ref.)
	Hypertension	1739/9387	1.861(1.742-1.988)	1.702(1.589-1.823)	1.701(1.588-1.822)	1.683(1.571-1.803)
	P-value		<0.001	<0.001	<0.001	<0.001

¹Adjusted for gender and age in mode 1; adjusted for smoking, drinking, BMI, labor intensity, diabetes in mode 2 based on mode 1; adjusted for highest education, marital status and household income in mode 3 based on mode 2; adjusted for parental history of stroke and heart attack in mode 4 based on mode 3.

²Cases refer to the number of cases of cardio-cerebrovascular disease, CVD, MACE or stroke; N refers to the number of total population.

³CVD, cardiovascular disease; MACE, major adverse cardiovascular events.

⁴P < 0.05 is considered statistically significant.