Table 3. Adjusted associations of carotid measurements with self-reported alcohol intake in male current drinkers.
Male current drinkers, n=2905 | Effect per 280 g/week usual alcohol (95% CI) | P-value |
---|---|---|
cIMT, mm | ||
Main model | 0.001 (-0.012, 0.013) | 0.930 |
+SBP | -0.006 (-0.018, 0.006) | 0.340 |
+SBP and BMI | -0.006 (-0.017, 0.006) | 0.361 |
+SBP, BMI and LDL-C | -0.002 (-0.015, 0.012) | 0.799 |
Main model including prior CVD | 0.002 (-0.015, 0.010) | 0.696 |
Carotid plaque (OR) | ||
Main model | 1.42 (1.14, 1.76) | 0.002 |
+SBP | 1.32 (1.06, 1.64) | 0.013 |
+SBP and BMI | 1.32 (1.06, 1.64) | 0.013 |
+SBP, BMI and LDL-C | 1.49 (1.16, 1.91) | 0.002 |
Main model including prior CVD | 1.37 (1.11, 1.68) | 0.003 |
Carotid plaque burden, mm | ||
Main model | 0.19 (0.10, 0.28) | <0.001 |
+SBP | 0.15 (0.07, 0.24) | <0.001 |
+SBP and BMI | 0.15 (0.06, 0.24) | <0.001 |
+SBP, BMI and LDL-C | 0.20 (0.10, 0.30) | <0.001 |
Main model including prior CVD | 0.18 (0.09, 0.27) | <0.001 |
Main model was adjusted for age, area, education, household income, and smoking, and participants with self-reported history of cardiovascular disease at baseline or resurvey were excluded. Participants with missing LDLC data were excluded from models adjusted for LDL-C. cIMT: carotid intima media thickness; SBP: systolic blood pressure; BMI: body mass index; LDL-C: low-density lipoprotein cholesterol; OR: odds ratio; CI: confidence interval