Table 2. Within group summary table of top 5 strongest Pearson’s r correlations between region-of-interest parameters and Progressive Supranuclear Palsy Rating Scale (PSP-RS), temporal stage and survival from scan.

	All (n=80)			Path (n=28)			Richardson’s Syndrome (n=62)			Cortical (n=7)			Subcortical (n=11)
Marker	Region	r	p-value	Region	r	p-value	Region	r	p-value	Region	r	p-value	Region	r	p-value
PSP-RS
	Left frontal area	-0.351	<0.001	Left frontal area	-0.653	<0.001	Left cerebellum volume	-0.392	<0.001	Left frontal area	-0.756	0.026	Left temporal thickness	-0.764	<0.001
	Left cerebellum volume	-0.340	<0.001	Left ventral diencephalon volume	-0.648	<0.001	Right cerebellum volume	-0.375	<0.001	Left frontal volume	-0.752	0.036	Left insula volume	-0.666	0.009
	Right cerebellum volume	-0.321	<0.001	Left thalamus volume	-0.643	<0.001	Midbrain volume	-0.325	0.002	Right cingulate area	-0.734	0.026	Right cingulate volume	-0.640	0.009
	Right cingulate area	-0.316	<0.001	Left temporal area	-0.625	<0.001	Right cingulate area	-0.319	0.004	Left temporal area	-0.679	0.043	Right frontal volume	-0.629	0.009
	Right frontal area	-0.314	<0.001	Left putamen volume	-0.618	<0.001	Superior cerebellar peduncle volume	-0.294	0.006	Right frontal volume	-0.629	0.088	Left frontal volume	-0.613	0.009
Temporal Stage
	Left accumbens volume	-0.328	<0.001	Left accumbens volume	-0.545	<0.001	Left accumbens volume	-0.284	0.002	Left occipital thickness	-0.858	<0.001	Right putamen volume	-0.754	<0.001
	Left amygdala volume	-0.217	0.009	Left temporal thickness	-0.402	0.002	Left amygdala volume	-0.264	0.002	Left parietal thickness	-0.806	<0.001	Right parietal thickness	-0.690	<0.001
	Left cerebellum volume	-0.214	0.008	Left temporal volume	-0.401	0.002	Left cerebellum volume	-0.217	0.012	Left frontal thickness	-0.765	<0.001	Right ventral diencephalon volume	-0.682	<0.001
	Right putamen volume	-0.200	0.012	Right temporal thickness	-0.386	0.002	Right putamen volume	-0.202	0.020	Right frontal thickness	-0.705	0.001	Left occipital volume	-0.648	<0.001
	Left putamen volume	-0.194	0.012	Left putamen volume	-0.381	0.003	Left putamen volume	-0.191	0.029	Right occipital thickness	-0.700	0.001	Right accumbens volume	-0.625	0.002
Survival from Scan
	Left accumbens volume	0.353	<0.001	Left accumbensvolume	0.538	<0.001	Left accumbens volume	0.397	<0.001	Right frontal thickness	0.779	<0.001	Right frontal thickness	0.677	<0.001
	Left cerebellum volume	0.253	<0.001	Right insula thickness	0.372	0.007	Left putamen volume	0.311	<0.001	Left temporal thickness	0.755	<0.001	Right insula thickness	0.546	0.005
	Right insula thickness	0.251	0.001	Left temporal thickness	0.350	0.007	Left cerebellum volume	0.288	<0.001	Left parietal thickness	0.709	0.002	Left frontal thickness	0.544	0.005
	Left putamen volume	0.247	0.001	Left putamen volume	0.305	0.024	Left amygdala volume	0.276	<0.001	Left frontal thickness	0.690	0.002	Left insula thickness	0.398	0.072
	Right putamen volume	0.210	0.005	Right temporal thickness	0.290	0.031	Left ventral diencephalon volume	0.266	<0.001	Right insula thickness	0.655	0.004	Left parietal thickness	0.366	0.081