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. Author manuscript; available in PMC: 2023 Dec 8.
Published in final edited form as: Nat Cardiovasc Res. 2023 Aug 31;2:835–852. doi: 10.1038/s44161-023-00325-8

Extended Data Fig. 6. Validation of shotgun lipidomics data by targeted RPLC-MS/MS. Related to Figure 4.

Extended Data Fig. 6

Trends of selected class representative lipid species were confirmed by targeted reverse-phase LC-MS/MS. Shown in blue are data obtained from shotgun measurements, shown in grey are results from LC experiments. For better comparison of observed lipid trends, lipid quantities are shown as relative amount compared to day 1. All data show the mean of 3 biological replicates. One biological replicate was comprised of 5 individual animals. Error bars represent standard deviations.