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. Author manuscript; available in PMC: 2024 Jan 11.
Published in final edited form as: Small. 2022 Jun 30;18(36):e2202303. doi: 10.1002/smll.202202303

Figure 7.

Figure 7

a) Images of cell types studied and b) their level of CD44 expression receptor. Scale bars represent 200 μm. Bars represent the mean ± SEM (N = 3). c) Transfection efficiency and d) viability of distinct cell types transfected with nanoneedles coated with 4-polyplex nanofilms. Bars represent the mean ± SEM (N = 3). Statistical significance as (**) p < 0.01, (***) p < 0.001 and (****) p < 0.0001, using one-way ANOVA and Sidak’s test. e) Transfection efficiency of COS-7 cells before and after blocking of receptor CD44, using hyaluronate-chitosan-polyplex coated nanoneedles and f) alginate-chitosan-polyplex coated nanoneedles. Bars represent the mean ± SEM (N = 3–8). Statistical significance as (*) p < 0.05, using a two-tailed t-test. (ns) non-statistical difference.