Figure 4. Distribution of known phosphorylation sites on LIR motifs on some mammalian Atg8-interacting proteins.

Known positive (green circle with plus sign) or negative effects (red circle with minus sign) of phosphorylation (blue circle) of a particular residue relative to binding to Atg8s indicated. Yellow circle and half-filled green circle with plus sign indicate no regulation of ATG8 binding and positive effect specific to LC3 subfamily binding, respectively. The actual proteins are shown below each site. See also Table 1.