Table 2.

Multivariable logistic regression of variables associated with seeking healthcare during the RCT. Adapted from Greer 2022.¹⁸

Variable	Additional healthcare sought during the study period
	aOR* (95% CI)	P value
Country
Myanmar patients	Reference
Thai patients	0.43 (0.23 to 0.81)	0.008
Sought healthcare before enrolment	1.47 (1.07 to 2.01)	0.016
Documented fever at enrolment	1.75 (1.31 to 2.35)	<0.001
Self-reported symptom severity score (1 point increase)	1.81 (1.33 to 2.46)	<0.001
Diagnosis at enrolment#
RTIs	Reference
Other infections	1.22 (0.70 to 2.12)	0.480
Acute viral infections (unspecified)	1.71 (1.12 to 2.63)	0.014
Dual infection	1.82 (1.04 to 3.18)	0.037
CRP level at enrolment (1 mg/L increase)	1.01 (1.00 to 1.01)	0.001
Antibiotics prescribed at enrolment	0.52 (0.37 to 0.73)	<0.001

^*The study site was added as a random effect. #Other infections include all non-RTIs affecting other systems such as gastrointestinal and skin infections. Acute viral infection was a common diagnosis made in Myanmar alongside RTIs, common symptoms included cough and runny nose but some patients had fever as the sole symptom. Dual infections include a diagnosis from two of the diagnosis categories.