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. Author manuscript; available in PMC: 2024 Feb 24.
Published in final edited form as: Front Trop Dis. 2023 Mar 1;4:1102265. doi: 10.3389/fitd.2023.1102265

Figure 4.

Figure 4

Location of polymorphisms on the 3D structure. Shows the SNPs identified that fall within the protein-protein and protein- basigin interaction regions of the Rh5 (brown), CyRPA (green) and Ripr (purple) protein complex. Polymorphic residues C203Y identified on Rh5 protein and F292V on CyRPA are highlighted in green and yellow, respectively. The Rh5 C203 mutation falls within the Basigin-Rh5 protein interaction region, while the CyRPA F292 mutation is located on blade 6, Ripr – CyRPA proteins interaction region.