Table 1. List of high frequency SNPs identified in Lake Victoria and Kilifi parasite population.

Gene	Position	Ref	Alt	S/NS	Lake Victoria (n=26)	Kilifi (n=68)	MalariaGEN global dataset (n=7,113)
pfripr	pfripr_190	V	A	NS	7.7	10.3	+
	pfripr_226*	Y	H	NS	3.8	0	+
	pfripr_236*	F	V	NS	3.8	0	-
	pfripr_255	M	I	NS	7.7	2.8	-
	pfripr_259	Y	H	NS	23.1	23.6	+
	pfripr_441*	T	N	NS	3.8	0	-
	pfripr_1003	A	S	NS	7.7	10.3	+
pfrh5	pfrh_147	Y	H	NS	7.7	22.6	+
	pfrh_148	H	D	NS	7.7	22.6	+
	pfrh_203	C	Y	NS	42.3	10.3	+
	pfrh_277	S	N	NS	7.7	0	-
	pfrh_371*	V	I	NS	3.8	4.1	+
	pfrh_407*	I	V	NS	3.8	0.7	+
	pfrh_410	I	M	NS	7.7	3.4	+
	pfrh_429	K	N	NS	34.6	34.9	+
pfcyrpa	pfcyrpa_25*	S	N	NS	3.8	0	-
	pfcyrpa_236*	D	N	NS	3.8	3.4	-
	pfcyrpa_292*	V	F	NS	3.8	0	+
pfp113	pfp113_17*	L	V	NS	3.8	0	-
	pfp113_234*	E	K	NS	3.8	1.4	+
	pfp113_620*	Q	H	S	3.8	0	-
	pfp113_857*	Q	E	NS	3.8	0	-

Polymorphisms identified in both populations and the global MalariaGEN dataset are indicated with a plus +, and singleton SNPs are indicated by an asterisk*.

Ref refers to the 3D7 Plasmodium falciparum strain reference amino acid, while Alt refers to the amino acid variation. The SNPs are classified under S (synonymous or NS (non-synonymous) and frequency of SNPs is expressed as percentages.