Effects of increasing inhibitor concentrations on susceptible and resistant p7 proteins. Effects of increasing concentrations (0, 0.1, 0.5, 1, 2, and 5 μM) of amantadine, rimantadine, and NN-DNJ on activity of J4 and JFH-1 recombinant p7 activity in liposome dye release were measured as % of untreated initial rate. Results are an average of three experiments with each condition in triplicate. Error bars represent standard errors of the mean.