Table 3. Features present on initial CTPA at time of PE diagnosis in patients with subsequent diagnosis of CTEPH and a randomly selected control group of patients not diagnosed with CTEPH.
| CTEPH +ve (n=36) |
CTEPH -ve (n=36) |
|
|---|---|---|
| Demographics: | ||
| Age, years (mean ± SD) | 69.9 ± 13.9 | 68.5 ± 11.95 |
| Sex M/F n, (%) | 18 (50)/18 (50) | 16 (44)/20(56) |
| Features suggestive of PH: | ||
| PA ≥ 30mm n, (%) | 24 (67) | 11 (31) |
| RV:LV ≥1 n, (%) | 28 (78) | 13 (36) |
| RVOTH ≥6mm n, (%) | 16 (44) | 3 (8) |
| All 3 features suggestive of PH present n, (%) | 13 (36) | 2 (6) |
| Features suggestive of CTEPD: | ||
| Dilated bronchial arteries, yes/no (%)* | 10 (28) | 2 (6) |
| Arterial webs or bands, yes/no (%) | 4 (11) | 1 (3) |
| Attenuated or Occluded vessels combined, n (%) | 13 (36) | 1 (3) |
| Mosaic parenchymal perfusion pattern yes/no n, (%) | 8 (22) | 2 (6) |
| 2 or more features suggestive of CTEPD n, (%) | 12 (33) | 1 (3) |
| Features suggestive of CTEPH at index event: | ||
| 3 features of PH and ≥ 2 features of CTEPD n, (%) | 7 (19) | 0 (0) |
PA=pulmonary artery; RV:LV=right to left ventricular ratio; RVOTH=right ventricular outflow tract hypertrophy; PH=pulmonary hypertension; CTEPD=chronic thromboembolic pulmonary disease; CTEPH=chronic thromboembolic pulmonary hypertension.
CTPA at the time of diagnosis of sufficient diagnostic quality were available for review in 36/41 of CTEPH +ve patients and are compared to a randomly selected control group of 36 patients not diagnosed as having CTEPH during the conduct of the study. PA pulmonary artery diameter; RV:LV ratio of internal right ventricular to left ventricular diameter; RVOTH thickness of right ventricular outflow tract.
assessment of bronchial artery size was not possible due to lack of contrast opacification in 9 (25%) of CTEPH +ve patients and 6 (17%) of CTEPH -ve patients